Assay Detail
Functional
CHEMBL1272811
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Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumour activity of glycyrrhetinic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.08 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1269524 | — | — | 1 | 5.60 |
| CHEMBL1269535 | — | — | 1 | 5.55 |
| CHEMBL1269521 | — | — | 1 | 5.54 |
| CHEMBL1269537 | — | — | 1 | 5.46 |
| CHEMBL1269536 | — | — | 1 | 5.36 |
| CHEMBL1269527 | — | — | 1 | 5.34 |
| CHEMBL1269516 | — | — | 1 | 4.94 |
| CHEMBL1271592 | — | — | 1 | 4.80 |
| CHEMBL1271536 | — | — | 1 | 4.66 |
| CHEMBL1271483 | — | — | 1 | 4.56 |
| CHEMBL230006 | ENOXOLONE | 2.0 | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1269524 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL1269535 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL1269521 | — | IC50 | = | 2870.0 | nM | 5.54 |
| CHEMBL1269537 | — | IC50 | = | 3470.0 | nM | 5.46 |
| CHEMBL1269536 | — | IC50 | = | 4380.0 | nM | 5.36 |
| CHEMBL1269527 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL1269516 | — | IC50 | = | 11480.0 | nM | 4.94 |
| CHEMBL1271592 | — | IC50 | = | 15970.0 | nM | 4.80 |
| CHEMBL1271536 | — | IC50 | = | 22140.0 | nM | 4.66 |
| CHEMBL1271483 | — | IC50 | = | 27540.0 | nM | 4.56 |
| CHEMBL230006 | ENOXOLONE | IC50 | = | 80090.0 | nM | 4.10 |