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Assay Detail

CHEMBL1273267

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine factor 10a
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL3656)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Factor Xa inhibitors: next-generation antithrombotic agents.
Pinto DJ, Smallheer JM, Cheney DL, Knabb RM, Wexler RR.
J Med Chem (2010) 53 : 6243 -6274
PubMed 20503967 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.21 6.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48233 1 6.21
CHEMBL279962 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48233 Ki = 610.0 nM 6.21
CHEMBL279962 Ki = 570.0 nM -