Assay Detail
Binding
CHEMBL1273508
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H](S)-warfarin from methacrylic acid-ethylene dimethacrylate copolymer
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthetic human serum albumin Sudlow I binding site mimics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.05 | 4.05 |
| logEC50 | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1464 | WARFARIN | 4.0 | 2 | 4.05 |
| CHEMBL1272169 | COUMACHLOR | — | 2 | - |
| CHEMBL6466 | COUMARIN | 4.0 | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1464 | WARFARIN | EC50 | = | 89600.0 | nM | 4.05 |
| CHEMBL1272169 | COUMACHLOR | EC50 | = | 165000.0 | nM | - |
| CHEMBL6466 | COUMARIN | EC50 | = | 1290000.0 | nM | - |
| CHEMBL1464 | WARFARIN | logEC50 | = | -4.05 | — | - |
| CHEMBL1272169 | COUMACHLOR | logEC50 | = | -3.78 | — | - |
| CHEMBL6466 | COUMARIN | logEC50 | = | -2.89 | — | - |