Assay Detail
Binding
CHEMBL1274065
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Displacement of (-)-[3H]DTG from sigma 2 receptor in rat liver membranes after 120 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.51 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1271906 | — | — | 1 | 6.64 |
| CHEMBL1271961 | — | — | 1 | 6.60 |
| CHEMBL1271907 | — | — | 1 | 6.28 |
| CHEMBL1271793 | — | — | 1 | - |
| CHEMBL1271850 | — | — | 1 | - |
| CHEMBL65239 | — | — | 1 | - |
| CHEMBL277630 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1271906 | — | Ki | = | 229.0 | nM | 6.64 |
| CHEMBL1271961 | — | Ki | = | 252.0 | nM | 6.60 |
| CHEMBL1271907 | — | Ki | = | 526.0 | nM | 6.28 |
| CHEMBL1271793 | — | Ki | - | — | - | |
| CHEMBL1271850 | — | Ki | - | — | - | |
| CHEMBL65239 | — | Ki | - | — | - | |
| CHEMBL277630 | — | Ki | - | — | - |