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Assay Detail

CHEMBL1274075

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Binding
Inhibition of Helix pomatia beta-mannosidase after 10 to 30 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Helix pomatia
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.
Aguilar-Moncayo M, García-Moreno MI, Stütz AE, García Fernández JM, Wrodnigg TM, Ortiz Mellet C.
Bioorg Med Chem (2010) 18 : 7439 -7445
PubMed 20889348 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 5 4.96 4.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1272019 1 4.96
CHEMBL1271962 1 -
CHEMBL1272018 1 -
CHEMBL1269789 1 -
CHEMBL1269790 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1272019 Ki = 11000.0 nM 4.96
CHEMBL1271962 Ki - -
CHEMBL1272018 Ki = 387000.0 nM -
CHEMBL1269789 Ki = 522000.0 nM -
CHEMBL1269790 Ki = 186000.0 nM -