Assay Detail
Binding
CHEMBL1280219
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Inhibition of Pseudomonas aeruginosa VIM-1 beta-lactamase after 10 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.52 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL858 | EDETIC ACID | 3.0 | 1 | 5.03 |
| CHEMBL284104 | DIPICOLINIC ACID | — | 1 | 4.38 |
| CHEMBL415879 | PHENANTHROLINE | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL858 | EDETIC ACID | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL284104 | DIPICOLINIC ACID | IC50 | = | 41600.0 | nM | 4.38 |
| CHEMBL415879 | PHENANTHROLINE | IC50 | = | 73000.0 | nM | 4.14 |