Assay Detail
Binding
CHEMBL1280269
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Binding affinity to Candida albicans CYP56 by spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
CYP56 (Dit2p) in Candida albicans: characterization and investigation of its role in growth and antifungal drug susceptibility.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.64 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL64391 | ITRACONAZOLE | 4.0 | 1 | 7.00 |
| CHEMBL106 | FLUCONAZOLE | 4.0 | 1 | 6.64 |
| CHEMBL638 | VORICONAZOLE | 4.0 | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL64391 | ITRACONAZOLE | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL106 | FLUCONAZOLE | Kd | = | 230.0 | nM | 6.64 |
| CHEMBL638 | VORICONAZOLE | Kd | = | 510.0 | nM | 6.29 |