Assay Detail
Binding
CHEMBL1281317
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli DNA gyrase by gel electrophoresis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.35 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | 4.0 | 1 | 7.00 |
| CHEMBL36506 | NOVOBIOCIN | 4.0 | 1 | 7.00 |
| CHEMBL1276315 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL36506 | NOVOBIOCIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1276315 | — | IC50 | = | 9000.0 | nM | 5.05 |