Assay Detail

CHEMBL1282134

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of Escherichia coli Inhibitor-resistant beta-lactamase SHV-56

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Escherichia coli
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.

Dubois V, Poirel L, Demarthe F, Arpin C, Coulange L, Minarini LA, Bezian MC, Nordmann P, Quentin C.
Antimicrob Agents Chemother (2008) 52 : 3792 -3794
PubMed 18663019 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.52	6.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL403	SULBACTAM	4.0	1	6.52

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL403	SULBACTAM	IC50	=	300.0	nM	6.52