Assay Detail
Binding
CHEMBL1282584
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Inhibition of Human cytomegalovirus pUL97 assessed as inhibition of phosphorylation of 100 to 1000 uM cyclopropavir
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human betaherpesvirus 5 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine protein kinase UL97 (CHEMBL1287608) ↗| Type | SINGLE PROTEIN |
| Organism | Human herpesvirus 5 |
Publication
Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | 2.0 | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | Ki | = | 3.0 | nM | 8.52 |