Assay Detail
Functional
CHEMBL1282585
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Antiviral activity against Human cytomegalovirus
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.87 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | 2.0 | 1 | 6.34 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | EC50 | = | 460.0 | nM | 6.34 |
| CHEMBL182 | GANCICLOVIR | EC50 | = | 4100.0 | nM | 5.39 |