Assay Detail
Binding
CHEMBL1282589
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Binding affinity to amyloid beta (1 to 40)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 5.69 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93334 | — | — | 1 | 6.52 |
| CHEMBL1275978 | — | — | 1 | 5.95 |
| CHEMBL1275946 | — | — | 1 | 5.74 |
| CHEMBL224392 | THIOFLAVIN T | — | 1 | 5.64 |
| CHEMBL1275945 | — | — | 1 | 5.54 |
| CHEMBL1275979 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93334 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL1275978 | — | Kd | = | 1130.0 | nM | 5.95 |
| CHEMBL1275946 | — | Kd | = | 1840.0 | nM | 5.74 |
| CHEMBL224392 | THIOFLAVIN T | Kd | = | 2300.0 | nM | 5.64 |
| CHEMBL1275945 | — | Kd | = | 2890.0 | nM | 5.54 |
| CHEMBL1275979 | — | Kd | = | 17900.0 | nM | 4.75 |