Assay Detail
Functional
CHEMBL1283085
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Antileishmanial activity against antimony resistant Leishmania donovani MC4-R infected in mouse J774 macrophage
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel arylimidamides for treatment of visceral leishmaniasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.10 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1275764 | — | — | 1 | 7.12 |
| CHEMBL1276549 | — | — | 1 | 6.82 |
| CHEMBL2079699 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1275764 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL1276549 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL2079699 | — | IC50 | = | 44000.0 | nM | 4.36 |