Assay Detail
Functional
CHEMBL1283374
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Antimalarial activity against Plasmodium falciparum W2 assessed as inhibition of [3H]hypoxanthine uptake organism selected on 80 ng/mL compound concentration
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.64 | 7.64 |
| IC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1208264 | ARTELINIC ACID | — | 2 | 7.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1208264 | ARTELINIC ACID | IC50 | = | 22.75 | nM | 7.64 |
| CHEMBL1208264 | ARTELINIC ACID | IC90 | = | 56.8 | nM | - |