Assay Detail
Binding
CHEMBL1285368
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human recombinant renin by isothermal titration calorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Direct renin inhibitors as a new therapy for hypertension.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.84 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1234021 | — | — | 1 | 7.10 |
| CHEMBL1276281 | — | — | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1234021 | — | Kd | = | 79.0 | nM | 7.10 |
| CHEMBL1276281 | — | Kd | = | 270.0 | nM | 6.57 |