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Assay Detail

CHEMBL1285370

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of cathepsin D
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cathepsin D (CHEMBL2581)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Direct renin inhibitors as a new therapy for hypertension.
Webb RL, Schiering N, Sedrani R, Maibaum J.
J Med Chem (2010) 53 : 7490 -7520
PubMed 20731374 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL509903 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL509903 IC50 = 2700.0 nM 5.57