Assay Detail
Binding
CHEMBL1285541
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Selectivity ratio of IC50 for human recombinant CD38 to IC50 for Schistosoma mansoni recombinant NAD+ glycohydrolase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.83 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257839 | KUROMANIN | — | 1 | 5.20 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 5.09 |
| CHEMBL1275624 | PETUNIDIN | — | 1 | 4.79 |
| CHEMBL404515 | CYANIDIN | — | 1 | 4.66 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257839 | KUROMANIN | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL151 | LUTEOLIN | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL1275624 | PETUNIDIN | IC50 | = | 16300.0 | nM | 4.79 |
| CHEMBL404515 | CYANIDIN | IC50 | = | 21800.0 | nM | 4.66 |
| CHEMBL50 | QUERCETIN | IC50 | = | 37900.0 | nM | 4.42 |