Assay Detail
Binding
CHEMBL1285707
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Binding affinity to 5HT3A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Computational analysis of ligand recognition sites of homo- and heteropentameric 5-HT3 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.45 | 10.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1189679 | PALONOSETRON | 4.0 | 1 | 10.50 |
| CHEMBL289469 | GRANISETRON | 4.0 | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1189679 | PALONOSETRON | Ki | = | 0.03162 | nM | 10.50 |
| CHEMBL289469 | GRANISETRON | Ki | = | 3.981 | nM | 8.40 |