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Assay Detail

CHEMBL1286503

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Functional
Antibacterial activity against Chlamydia pneumoniae CWL029 infected in human HL cells after 72 hrs by TR-FIA method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Chlamydia pneumoniae
Cell Type HL
Confidence 1 — Organism
Curated By Autocuration

Target

Chlamydia pneumoniae (CHEMBL612694)
Type ORGANISM
Organism Chlamydia pneumoniae

Publication

Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae.
Keurulainen L, Salin O, Siiskonen A, Kern JM, Alvesalo J, Kiuru P, Maass M, Yli-Kauhaluoma J, Vuorela P.
J Med Chem (2010) 53 : 7664 -7674
PubMed 20932010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.61 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1276927 1 5.70
CHEMBL1276928 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1276927 IC50 = 2000.0 nM 5.70
CHEMBL1276928 IC50 = 3000.0 nM 5.52