Assay Detail
Binding
CHEMBL1286681
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Binding affinity to bovine adenosine A3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL335950 | — | — | 1 | 6.52 |
| CHEMBL136689 | — | — | 1 | - |
| CHEMBL112756 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL335950 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL136689 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL112756 | — | Ki | > | 1000.0 | nM | - |