Assay Detail
Functional
CHEMBL1614178
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Radioactive Cell-Free Dose Screen to Characterize Inhibitors of Polyadenylation In Vitro Using Saccharomyces cerevisiae Extracts. (Class of assay: confirmatory) [Related pubchem assays: 1875 (Primary HTS to identify potential inhibitors of polyadenylation)]
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 4.80 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL578063 | ALAZANINE | 2.0 | 1 | 4.80 |
| CHEMBL1380339 | — | — | 1 | - |
| CHEMBL1553474 | — | — | 1 | - |
| CHEMBL1589724 | — | — | 1 | - |
| CHEMBL1322375 | — | — | 1 | - |
| CHEMBL1411595 | — | — | 1 | - |
| CHEMBL1453322 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL578063 | ALAZANINE | EC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL1380339 | — | EC50 | = | 410000.0 | nM | - |
| CHEMBL1553474 | — | EC50 | = | 700000.0 | nM | - |
| CHEMBL1589724 | — | EC50 | = | 1100000.0 | nM | - |
| CHEMBL1322375 | — | EC50 | = | 400000.0 | nM | - |
| CHEMBL1411595 | — | EC50 | = | 900000.0 | nM | - |
| CHEMBL1453322 | — | EC50 | = | 280000.0 | nM | - |