Assay Detail
Functional
CHEMBL1614411
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: SAR analysis of NF-kappaB dependent luciferase using Doxorubicin as an inducer - Set 2. (Class of assay: confirmatory) [Related pubchem assays: 1578, 1575 (Summary AID.)]
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nucleotide-binding oligomerization domain-containing protein 1 (CHEMBL1293222) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 16 | 5.23 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1444568 | — | — | 1 | 5.23 |
| CHEMBL1299367 | — | — | 1 | - |
| CHEMBL1345225 | — | — | 1 | - |
| CHEMBL1305184 | — | — | 1 | - |
| CHEMBL1595049 | — | — | 1 | - |
| CHEMBL1386167 | — | — | 1 | - |
| CHEMBL1419822 | — | — | 1 | - |
| CHEMBL1336829 | — | — | 1 | - |
| CHEMBL1331314 | — | — | 1 | - |
| CHEMBL1567543 | — | — | 1 | - |
| CHEMBL1448844 | — | — | 1 | - |
| CHEMBL1468879 | — | — | 1 | - |
| CHEMBL1519375 | — | — | 1 | - |
| CHEMBL1488993 | — | — | 1 | - |
| CHEMBL1491481 | — | — | 1 | - |
| CHEMBL1452157 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1444568 | — | IC50 | = | 5939.0 | nM | 5.23 |
| CHEMBL1299367 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1345225 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1305184 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1595049 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1386167 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1419822 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1336829 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1331314 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1567543 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1448844 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1468879 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1519375 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1488993 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1491481 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1452157 | — | IC50 | > | 25000.0 | nM | - |