Assay Detail
Functional
CHEMBL1614412
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Dose Response Confirmation for DnaK Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 547 (Screening assay preceding this dose-response confirmation assay.)]
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli str. K-12 substr. MG1655 |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.63 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1365553 | — | — | 2 | 6.26 |
| CHEMBL1256813 | — | — | 2 | 6.08 |
| CHEMBL1256623 | — | — | 2 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1365553 | — | IC50 | = | 550.58 | nM | 6.26 |
| CHEMBL1256813 | — | IC50 | = | 837.09 | nM | 6.08 |
| CHEMBL1256813 | — | IC50 | = | 1624.86 | nM | 5.79 |
| CHEMBL1365553 | — | IC50 | = | 1664.33 | nM | 5.78 |
| CHEMBL1256623 | — | IC50 | = | 3921.72 | nM | 5.41 |
| CHEMBL1256623 | — | IC50 | = | 36310.06 | nM | 4.44 |