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Assay Detail

CHEMBL1614524

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to DRD Non-Viral Oncogenic Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)]
ChEMBL ↗
1147
Total Activities
1147
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Category confirmatory
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545) ↗
Type UNCHECKED

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1147 5.31 6.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1345159 — — 1 6.76
CHEMBL1520346 — — 1 6.73
CHEMBL1483593 — — 1 6.70
CHEMBL486504 N-ACETYLCOLCHINOL -1.0 1 6.70
CHEMBL1498488 — — 1 6.66
CHEMBL1321427 — — 1 6.65
CHEMBL1376974 — — 1 6.61
CHEMBL1389248 — — 1 6.61
CHEMBL1524921 — — 1 6.56
CHEMBL1467533 — — 1 6.55
CHEMBL1424118 — — 1 6.54
CHEMBL3191874 — — 1 6.52
CHEMBL1566610 — — 1 6.48
CHEMBL1424468 — — 1 6.48
CHEMBL1200563 CERIVASTATIN SODIUM 4.0 1 6.47
CHEMBL1582760 — — 1 6.46
CHEMBL87 — — 1 6.46
CHEMBL1237061 PITAVASTATIN CALCIUM 4.0 1 6.45
CHEMBL1405453 — — 1 6.45
CHEMBL1392527 — — 1 6.45
CHEMBL1462630 — — 1 6.44
CHEMBL1488760 — — 1 6.44
CHEMBL1324197 — — 1 6.44
CHEMBL2359072 — — 1 6.44
CHEMBL1359872 — — 1 6.43
CHEMBL1451921 — — 1 6.43
CHEMBL1536118 — — 1 6.43
CHEMBL1970422 — — 1 6.43
CHEMBL1505209 — — 1 6.42
CHEMBL1545099 — — 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1345159 — EC50 = 174.0 nM 6.76
CHEMBL1520346 — EC50 = 185.0 nM 6.73
CHEMBL1483593 — EC50 = 202.0 nM 6.70
CHEMBL486504 N-ACETYLCOLCHINOL EC50 = 201.0 nM 6.70
CHEMBL1498488 — EC50 = 221.0 nM 6.66
CHEMBL1321427 — EC50 = 225.0 nM 6.65
CHEMBL1389248 — EC50 = 244.0 nM 6.61
CHEMBL1376974 — EC50 = 244.0 nM 6.61
CHEMBL1524921 — EC50 = 278.0 nM 6.56
CHEMBL1467533 — EC50 = 284.0 nM 6.55
CHEMBL1424118 — EC50 = 289.0 nM 6.54
CHEMBL3191874 — EC50 = 300.0 nM 6.52
CHEMBL1424468 — EC50 = 328.0 nM 6.48
CHEMBL1566610 — EC50 = 332.0 nM 6.48
CHEMBL1200563 CERIVASTATIN SODIUM EC50 = 338.0 nM 6.47
CHEMBL87 — EC50 = 351.0 nM 6.46
CHEMBL1582760 — EC50 = 347.0 nM 6.46
CHEMBL1405453 — EC50 = 358.0 nM 6.45
CHEMBL1237061 PITAVASTATIN CALCIUM EC50 = 353.0 nM 6.45
CHEMBL1392527 — EC50 = 358.0 nM 6.45
CHEMBL1324197 — EC50 = 362.0 nM 6.44
CHEMBL1462630 — EC50 = 362.0 nM 6.44
CHEMBL1488760 — EC50 = 360.0 nM 6.44
CHEMBL2359072 — EC50 = 361.0 nM 6.44
CHEMBL1970422 — EC50 = 372.0 nM 6.43
CHEMBL1536118 — EC50 = 373.0 nM 6.43
CHEMBL1359872 — EC50 = 374.0 nM 6.43
CHEMBL1451921 — EC50 = 375.0 nM 6.43
CHEMBL1505209 — EC50 = 383.0 nM 6.42
CHEMBL1545099 — EC50 = 381.0 nM 6.42
CHEMBL3198970 — EC50 = 387.0 nM 6.41
CHEMBL1445297 — EC50 = 388.0 nM 6.41
CHEMBL1490339 — EC50 = 400.0 nM 6.40
CHEMBL587994 — EC50 = 395.0 nM 6.40
CHEMBL1388358 — EC50 = 413.0 nM 6.38
CHEMBL1491893 — EC50 = 423.0 nM 6.37
CHEMBL1539486 — EC50 = 429.0 nM 6.37
CHEMBL3198544 — EC50 = 430.0 nM 6.37
CHEMBL1451736 — EC50 = 441.0 nM 6.36
CHEMBL1581197 — EC50 = 440.0 nM 6.36
CHEMBL1586733 — EC50 = 458.0 nM 6.34
CHEMBL3199311 — EC50 = 463.0 nM 6.33
CHEMBL1609770 — EC50 = 463.0 nM 6.33
CHEMBL1383090 — EC50 = 468.0 nM 6.33
CHEMBL1368103 — EC50 = 484.0 nM 6.32
CHEMBL1523841 — EC50 = 480.0 nM 6.32
CHEMBL1998716 — EC50 = 475.0 nM 6.32
CHEMBL1521217 — EC50 = 489.0 nM 6.31
CHEMBL1340058 — EC50 = 496.0 nM 6.30
CHEMBL1330793 — EC50 = 495.0 nM 6.30