Assay Detail
Functional
CHEMBL1614536
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1575, AID1578, AID2333]
25
Total Activities
24
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF-7/NOD1 |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 25 | 5.46 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1412853 | — | — | 2 | 6.26 |
| CHEMBL1419822 | — | — | 1 | 5.67 |
| CHEMBL1305184 | — | — | 1 | 5.48 |
| CHEMBL1519375 | — | — | 1 | 5.46 |
| CHEMBL1595049 | — | — | 1 | 5.39 |
| CHEMBL1488993 | — | — | 1 | 5.07 |
| CHEMBL1314048 | — | — | 1 | 4.92 |
| CHEMBL1333987 | — | — | 1 | 4.70 |
| CHEMBL1332003 | — | — | 1 | - |
| CHEMBL1331314 | — | — | 1 | - |
| CHEMBL1567543 | — | — | 1 | - |
| CHEMBL1410618 | — | — | 1 | - |
| CHEMBL1491481 | — | — | 1 | - |
| CHEMBL1448844 | — | — | 1 | - |
| CHEMBL1433326 | — | — | 1 | - |
| CHEMBL1444568 | — | — | 1 | - |
| CHEMBL1452157 | — | — | 1 | - |
| CHEMBL1386167 | — | — | 1 | - |
| CHEMBL1299367 | — | — | 1 | - |
| CHEMBL1434007 | — | — | 1 | - |
| CHEMBL1345225 | — | — | 1 | - |
| CHEMBL1468879 | — | — | 1 | - |
| CHEMBL1336829 | — | — | 1 | - |
| CHEMBL1554526 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1412853 | — | IC50 | = | 550.7 | nM | 6.26 |
| CHEMBL1412853 | — | IC50 | = | 596.0 | nM | 6.22 |
| CHEMBL1419822 | — | IC50 | = | 2156.0 | nM | 5.67 |
| CHEMBL1305184 | — | IC50 | = | 3310.0 | nM | 5.48 |
| CHEMBL1519375 | — | IC50 | = | 3430.0 | nM | 5.46 |
| CHEMBL1595049 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL1488993 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL1314048 | — | IC50 | = | 12110.0 | nM | 4.92 |
| CHEMBL1333987 | — | IC50 | = | 19790.0 | nM | 4.70 |
| CHEMBL1331314 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1567543 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1410618 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1491481 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1448844 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1433326 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1444568 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1336829 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1332003 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1386167 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1299367 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1434007 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1345225 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1468879 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1554526 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1452157 | — | IC50 | > | 25000.0 | nM | - |