Assay Detail
Binding
CHEMBL1633711
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Inhibition of beta-glucosidase using salicin substrate
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hydroxycoumarin derivatives: novel and potent α-glucosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.20 | 4.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12252 | 5,7-DIHYDROXY-4-METHYLCOUMARIN | — | 1 | 4.34 |
| CHEMBL1631883 | — | — | 1 | 4.06 |
| CHEMBL32810 | — | — | 1 | - |
| CHEMBL1631886 | — | — | 1 | - |
| CHEMBL1631887 | — | — | 1 | - |
| CHEMBL150372 | 3-HYDROXYCOUMARIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12252 | 5,7-DIHYDROXY-4-METHYLCOUMARIN | IC50 | = | 45400.0 | nM | 4.34 |
| CHEMBL1631883 | — | IC50 | = | 87600.0 | nM | 4.06 |
| CHEMBL32810 | — | IC50 | > | 400000.0 | nM | - |
| CHEMBL1631886 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL1631887 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL150372 | 3-HYDROXYCOUMARIN | IC50 | - | — | - |