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Assay Detail

CHEMBL1635532

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Monkeypox virus V1979-I-005 infected in african green monkey BSC-40 cells assessed as reduction in virus-induced cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Monkeypox virus
Cell Type BSC-40
Confidence 1 — Organism
Curated By Autocuration

Target

Monkeypox virus (CHEMBL613120)
Type ORGANISM
Organism Monkeypox virus

Publication

In vitro efficacy of ST246 against smallpox and monkeypox.
Smith SK, Olson VA, Karem KL, Jordan R, Hruby DE, Damon IK.
Antimicrob Agents Chemother (2009) 53 : 1007 -1012
PubMed 19075062 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.41 7.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1257073 TECOVIRIMAT 4.0 1 7.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1257073 TECOVIRIMAT EC50 = 39.0 nM 7.41