Assay Detail
Functional
CHEMBL1636227
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against GCV-resistant Human cytomegalovirus 759rD100 harboring 4-aa deletion (638-641) in UL97 kinase and DNA polymerase A987G mutant infected in human foreskin fibroblast by plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.05 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127498 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127498 | — | EC50 | = | 900.0 | nM | 6.05 |