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Assay Detail

CHEMBL1637017

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against Plasmodium falciparum Dd2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

In vitro and in vivo properties of ellagic acid in malaria treatment.
Soh PN, Witkowski B, Olagnier D, Nicolau ML, Garcia-Alvarez MC, Berry A, Benoit-Vical F.
Antimicrob Agents Chemother (2009) 53 : 1100 -1106
PubMed 19015354 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.26 7.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL269671 ARTEMISININ 3.0 1 7.87
CHEMBL6246 ELLAGIC ACID 2.0 1 6.98
CHEMBL76 CHLOROQUINE 4.0 1 6.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL269671 ARTEMISININ IC50 = 13.5 nM 7.87
CHEMBL6246 ELLAGIC ACID IC50 = 105.0 nM 6.98
CHEMBL76 CHLOROQUINE IC50 = 114.0 nM 6.94