Assay Detail
Functional
CHEMBL1637800
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Cytotoxicity against mouse L1210 cells after 24 hrs by MTT assay in presence of superoxide dismutase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.58 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096286 | — | — | 1 | 4.70 |
| CHEMBL1631408 | — | — | 1 | 4.52 |
| CHEMBL17200 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096286 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL1631408 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL17200 | — | IC50 | = | 31000.0 | nM | 4.51 |