Assay Detail
Binding
CHEMBL1638260
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Selectivity ratio of Ki for human Alpha-1D adrenoceptor to Ki for human alpha1B adrenoceptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and α1-adrenoceptor antagonist activity of tamsulosin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630938 | — | — | 1 | 8.00 |
| CHEMBL1630940 | — | — | 1 | 6.00 |
| CHEMBL1630939 | — | — | 1 | 6.00 |
| CHEMBL836 | TAMSULOSIN | 4.0 | 1 | 6.00 |
| CHEMBL1630941 | — | — | 1 | 4.00 |
| CHEMBL1630942 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630938 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1630940 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL1630939 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL836 | TAMSULOSIN | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL1630941 | — | Ki | = | 100000.0 | nM | 4.00 |
| CHEMBL1630942 | — | Ki | = | 10000000.0 | nM | - |