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Assay Detail

CHEMBL1640903

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Functional
Antimalarial activity against Plasmodium falciparum isolate 8948
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya.
Okombo J, Kiara SM, Rono J, Mwai L, Pole L, Ohuma E, Borrmann S, Ochola LI, Nzila A.
Antimicrob Agents Chemother (2010) 54 : 3302 -3307
PubMed 20516285 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.56 7.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL170 QUININE 4.0 1 7.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL170 QUININE IC50 = 27.8 nM 7.56