Assay Detail
Functional
CHEMBL1645783
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Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.08 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 6.17 |
| CHEMBL1644920 | — | — | 1 | 5.27 |
| CHEMBL1644919 | — | — | 1 | 5.17 |
| CHEMBL1644924 | — | — | 1 | 5.07 |
| CHEMBL1644925 | — | — | 1 | 4.97 |
| CHEMBL1644817 | EPICEANOTHIC ACID | — | 1 | 4.71 |
| CHEMBL1644923 | — | — | 1 | 4.18 |
| CHEMBL1644921 | — | — | 1 | - |
| CHEMBL1644922 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL1644920 | — | IC50 | = | 5320.0 | nM | 5.27 |
| CHEMBL1644919 | — | IC50 | = | 6750.0 | nM | 5.17 |
| CHEMBL1644924 | — | IC50 | = | 8510.0 | nM | 5.07 |
| CHEMBL1644925 | — | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL1644817 | EPICEANOTHIC ACID | IC50 | = | 19700.0 | nM | 4.71 |
| CHEMBL1644923 | — | IC50 | = | 66300.0 | nM | 4.18 |
| CHEMBL1644921 | — | IC50 | - | — | - | |
| CHEMBL1644922 | — | IC50 | - | — | - |