Assay Detail
Functional
CHEMBL1645785
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Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.20 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1644925 | — | — | 1 | 6.48 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 5.78 |
| CHEMBL1644924 | — | — | 1 | 4.49 |
| CHEMBL1644817 | EPICEANOTHIC ACID | — | 1 | 4.06 |
| CHEMBL1644919 | — | — | 1 | - |
| CHEMBL1644920 | — | — | 1 | - |
| CHEMBL1644921 | — | — | 1 | - |
| CHEMBL1644922 | — | — | 1 | - |
| CHEMBL1644923 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1644925 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 1650.0 | nM | 5.78 |
| CHEMBL1644924 | — | IC50 | = | 32500.0 | nM | 4.49 |
| CHEMBL1644817 | EPICEANOTHIC ACID | IC50 | = | 87200.0 | nM | 4.06 |
| CHEMBL1644919 | — | IC50 | = | 559600.0 | nM | - |
| CHEMBL1644920 | — | IC50 | = | 373600.0 | nM | - |
| CHEMBL1644921 | — | IC50 | = | 397500.0 | nM | - |
| CHEMBL1644922 | — | IC50 | = | 565300.0 | nM | - |
| CHEMBL1644923 | — | IC50 | = | 603500.0 | nM | - |