Assay Detail
Functional
CHEMBL1645787
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Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BGC-823 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.12 | 5.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 5.88 |
| CHEMBL1644817 | EPICEANOTHIC ACID | — | 1 | 5.62 |
| CHEMBL1644925 | — | — | 1 | 5.12 |
| CHEMBL1644920 | — | — | 1 | 5.02 |
| CHEMBL1644924 | — | — | 1 | 4.90 |
| CHEMBL1644921 | — | — | 1 | 4.71 |
| CHEMBL1644923 | — | — | 1 | 4.59 |
| CHEMBL1644919 | — | — | 1 | - |
| CHEMBL1644922 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL1644817 | EPICEANOTHIC ACID | IC50 | = | 2410.0 | nM | 5.62 |
| CHEMBL1644925 | — | IC50 | = | 7640.0 | nM | 5.12 |
| CHEMBL1644920 | — | IC50 | = | 9540.0 | nM | 5.02 |
| CHEMBL1644924 | — | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL1644921 | — | IC50 | = | 19300.0 | nM | 4.71 |
| CHEMBL1644923 | — | IC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL1644919 | — | IC50 | - | — | - | |
| CHEMBL1644922 | — | IC50 | - | — | - |