Assay Detail
Binding
CHEMBL1646432
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Inhibition of H2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.46 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643899 | — | — | 1 | 5.67 |
| CHEMBL1643900 | — | — | 1 | 5.35 |
| CHEMBL1643902 | — | — | 1 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643899 | — | Ki | = | 2148.0 | nM | 5.67 |
| CHEMBL1643900 | — | Ki | = | 4423.0 | nM | 5.35 |
| CHEMBL1643902 | — | Ki | = | 4450.0 | nM | 5.35 |