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Assay Detail

CHEMBL1646473

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SKOV3 cells after 72 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-OV-3
Confidence 1 — Organism
Curated By Autocuration

Target

SK-OV-3 (CHEMBL614925)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.
Lewin G, Shridhar NB, Aubert G, Thoret S, Dubois J, Cresteil T.
Bioorg Med Chem (2011) 19 : 186 -196
PubMed 21146994 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.55 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL18351 1 7.66
CHEMBL1643903 1 7.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL18351 IC50 = 22.0 nM 7.66
CHEMBL1643903 IC50 = 37.0 nM 7.43