Assay Detail
Binding
CHEMBL1647343
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Mycobacterium tuberculosis H37Rv CYP125A1 C429L mutant expressed in Escherichia coli by titration plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis H37Rv |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Steroid C26-monooxygenase (CHEMBL5629) ↗| Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
Publication
Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.78 | 5.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL474704 | — | — | 1 | 5.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL474704 | — | Kd | = | 1680.0 | nM | 5.78 |