Assay Detail
ADMET
CHEMBL1647814
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Growth inhibition of HUVEC cells after 20 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, in vitro and in vivo preliminary evaluation of anti-angiogenic properties of some pyrroloazaflavones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.00 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL192687 | — | — | 1 | 7.37 |
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 7.31 |
| CHEMBL364959 | — | — | 1 | 6.35 |
| CHEMBL1643580 | — | — | 1 | 5.38 |
| CHEMBL1643579 | — | — | 1 | 5.24 |
| CHEMBL191451 | — | — | 1 | 5.24 |
| CHEMBL1643581 | — | — | 1 | 5.09 |
| CHEMBL1643582 | — | — | 1 | - |
| CHEMBL192703 | — | — | 1 | - |
| CHEMBL1643583 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL192687 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL159 | VINBLASTINE | IC50 | = | 49.0 | nM | 7.31 |
| CHEMBL364959 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL1643580 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL1643579 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL191451 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL1643581 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL1643582 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL192703 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1643583 | — | IC50 | > | 10000.0 | nM | - |