Assay Detail
Binding
CHEMBL1647882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human carbonic anhydrase 2
10
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Correlation analyses on binding affinity of substituted benzenesulfonamides with carbonic anhydrase using ab initio MO calculations on their complex structures (II).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 7.91 | 8.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444536 | — | — | 2 | 8.86 |
| CHEMBL150043 | — | — | 2 | 8.30 |
| CHEMBL148660 | — | — | 2 | 7.77 |
| CHEMBL358263 | — | — | 2 | 7.53 |
| CHEMBL174847 | — | — | 2 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444536 | — | Ki | = | 1.38 | nM | 8.86 |
| CHEMBL150043 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL148660 | — | Ki | = | 16.98 | nM | 7.77 |
| CHEMBL358263 | — | Ki | = | 29.51 | nM | 7.53 |
| CHEMBL174847 | — | Ki | = | 81.28 | nM | 7.09 |
| CHEMBL358263 | — | Ki | = | 1.8620871366628655e+19 | nM | - |
| CHEMBL148660 | — | Ki | = | 3.981071705534986e+19 | nM | - |
| CHEMBL150043 | — | Ki | = | 2.0892961308540407e+20 | nM | - |
| CHEMBL444536 | — | Ki | = | 1.2022644346174083e+21 | nM | - |
| CHEMBL174847 | — | Ki | = | 4.570881896148752e+18 | nM | - |