Assay Detail
Binding
CHEMBL1648968
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]U69593 from kappa opioid receptor expressed in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.31 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL445332 | SALVINORIN A | 1.0 | 1 | 9.12 |
| CHEMBL1644775 | — | — | 1 | 7.38 |
| CHEMBL1644773 | — | — | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL445332 | SALVINORIN A | Ki | = | 0.75 | nM | 9.12 |
| CHEMBL1644775 | — | Ki | = | 42.0 | nM | 7.38 |
| CHEMBL1644773 | — | Ki | = | 3784.0 | nM | 5.42 |