Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1653255

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Coxsackievirus B5 infected in human RD cells assessed as protection against virus-induced cytopathogenicity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Coxsackievirus B5
Cell Type RD
Confidence 1 — Organism
Curated By Autocuration

Target

Coxsackievirus B5 (CHEMBL613555)
Type ORGANISM
Organism Coxsackievirus B5

Publication

Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71.
Chen TC, Chang HY, Lin PF, Chern JH, Hsu JT, Chang CY, Shih SR.
Antimicrob Agents Chemother (2009) 53 : 2740 -2747
PubMed 19414569 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL83661 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL83661 EC50 = 130.0 nM 6.89