Assay Detail
Binding
CHEMBL1655233
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Inhibition of calf placental adenosine deaminase by Lineweaver-Burk plot analysis
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 4.50 | 4.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL577902 | — | — | 1 | 4.94 |
| CHEMBL1651376 | — | — | 1 | 4.65 |
| CHEMBL1651369 | — | — | 1 | 4.61 |
| CHEMBL1651368 | — | — | 1 | 4.53 |
| CHEMBL1651370 | — | — | 1 | 4.49 |
| CHEMBL1651384 | — | — | 1 | 4.48 |
| CHEMBL285819 | — | — | 1 | 4.26 |
| CHEMBL516197 | — | — | 1 | 4.05 |
| CHEMBL1614817 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL577902 | — | Ki | = | 11400.0 | nM | 4.94 |
| CHEMBL1651376 | — | Ki | = | 22500.0 | nM | 4.65 |
| CHEMBL1651369 | — | Ki | = | 24300.0 | nM | 4.61 |
| CHEMBL1651368 | — | Ki | = | 29800.0 | nM | 4.53 |
| CHEMBL1651370 | — | Ki | = | 32100.0 | nM | 4.49 |
| CHEMBL1651384 | — | Ki | = | 33000.0 | nM | 4.48 |
| CHEMBL285819 | — | Ki | = | 54500.0 | nM | 4.26 |
| CHEMBL516197 | — | Ki | = | 89500.0 | nM | 4.05 |
| CHEMBL1614817 | — | Ki | = | 123000.0 | nM | - |