Assay Detail
Functional
CHEMBL1655347
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Antimalarial activity against Plasmodium falciparum
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.49 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1651832 | — | — | 1 | 6.60 |
| CHEMBL1651833 | — | — | 1 | 6.60 |
| CHEMBL1651834 | — | — | 1 | 6.60 |
| CHEMBL1651835 | — | — | 1 | 6.60 |
| CHEMBL1651836 | — | — | 1 | 6.60 |
| CHEMBL203125 | FOSMIDOMYCIN | 3.0 | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1651832 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1651833 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1651834 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1651835 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1651836 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL203125 | FOSMIDOMYCIN | EC50 | = | 1100.0 | nM | 5.96 |