Assay Detail
Functional
CHEMBL1658824
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against human cytomegalovirus AD169 infected in HFF after 8 to 10 days by plaque reduction assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.36 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.48 |
| CHEMBL1631219 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | EC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL1631219 | — | EC50 | = | 5850.0 | nM | 5.23 |