Assay Detail
Functional
CHEMBL1658856
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Antiviral activity against human cytomegalovirus 1117 harboring UL54 K513N mutant gene infected in HFF after 8 to 10 days by plaque reduction assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.09 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1631219 | — | — | 1 | 5.36 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1631219 | — | EC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL182 | GANCICLOVIR | EC50 | = | 15000.0 | nM | 4.82 |