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Assay Detail

CHEMBL1659313

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Echovirus type 11 infected in african green monkey BGMK cells assessed as inhibition of virus induced cytopathic effect after 18 to 24 hrs
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Echovirus E11
Cell Type BGMK
Confidence 1 — Organism
Curated By Autocuration

Target

Echovirus E11 (CHEMBL613751)
Type ORGANISM
Organism Echovirus E11

Publication

In vitro antiviral activity of V-073 against polioviruses.
Oberste MS, Moore D, Anderson B, Pallansch MA, Pevear DC, Collett MS.
Antimicrob Agents Chemother (2009) 53 : 4501 -4503
PubMed 19635956 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.06 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1235858 2 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1235858 EC50 = 9.0 nM 8.05
CHEMBL1235858 EC50 = 860.0 nM 6.07