Assay Detail
Binding
CHEMBL1662791
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Staphylococcus aureus ATCC 433000 PBP2a by Western blotting at pH 5.5 in presence of 100 uM Bocillin FL
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.13 | 5.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL520642 | CEFTOBIPROLE | 2.0 | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL520642 | CEFTOBIPROLE | IC50 | = | 7400.0 | nM | 5.13 |