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Assay Detail

CHEMBL1663964

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PC-3
Confidence 1 — Organism
Curated By Autocuration

Target

PC-3 (CHEMBL390)
Type CELL-LINE
Organism Homo sapiens

Publication

Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.
Marrazzo A, Fiorito J, Zappalà L, Prezzavento O, Ronsisvalle S, Pasquinucci L, Scoto GM, Bernardini R, Ronsisvalle G.
Eur J Med Chem (2011) 46 : 433 -438
PubMed 21055848 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.11 5.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1649601 1 5.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1649601 IC50 = 7800.0 nM 5.11