Assay Detail
Binding
CHEMBL1664439
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Polyunsaturated fatty acid 5-lipoxygenase (CHEMBL215) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identifying chelators for metalloprotein inhibitors using a fragment-based approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.54 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650615 | — | — | 1 | 4.96 |
| CHEMBL1461 | GENTISIC ACID | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650615 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL1461 | GENTISIC ACID | IC50 | = | 75000.0 | nM | 4.12 |